- Status: Closed
- Coordinator: Fondazione IRCCS Policlinico San Matteo, Pavia (IT)
- Area: Cardiology
- Start date: Friday, 01 January 2010
- Funding: EU
- Solutions: i2b2
The INHERITANCE project (Integrated Heart Research In Translational Genetics of Cardiomyopathies in Europe) is a multy-disciplinary, multi-centre research project funded by the European Commission, involving University of Pavia. The main task of the project is to investigate the molecular basis of Inherited Dilated cardiomyopathies (DCM) and to understand the impact and management of the condition within families that suffer from DCMs.
Figure 1 shows the data analysis architecture of the project. The patients'data collected by the clinical centers, are periodically uploaded, with an automatic procedure, into a data warehouse based on the i2b2 software system. The data are then made available to the researchers through a data mining and exploration tool. Literature is analyzed through a text mining strategy based on Natural Language Processing (NLP). Finally a decision support tool, exploiting the patient database, the text-mining tool and software solutions to automatically access biomedical databases, provides support in refining patient's diagnosis.Figura 1: The data analysis architecture of the Inheritance project
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