FSM - i2b2 Oncology

Additional Info

  • Status: Closed
  • Coordinator: IRCCS Fondazione Salvatore Maugeri, Pavia (IT)
  • Area: Oncology
  • Funding: Regione
  • Solutions: i2b2
  • Description:

    ONCO-i2b2 is an IT initiative of The University of Pavia and the IRCCS Fondazione Salvatore Maugeri of Pavia (FSM) to support clinical research in oncology. ONCO-i2b2, funded by the Lombardia region, grounds on the i2b2 software. Using i2b2 and new software modules purposely designed, data coming from multiple sources are integrated and jointly queried. The core of the integration process stands in retrieving and merging data from the biobank management software and from the FSM hospital information system. The integration process is based on a ontology of the problem domain and on open-source software integration modules. A Natural Language Processing module has been implemented, too. This module automatically extracts clinical information of oncology patients from unstructured medical records. The system currently manages more than two thousands patients and will be further implemented and improved in the next two years.


  • References:

    Segagni D, Tibollo V, Dagliati A, Zambelli A, Priori SG, Bellazzi R (2012) An ICT infrastructure to integrate clinical and molecular data in oncology research. BMC Bioinformatics 13(Suppl 4): S5. (linkpdf)

    Segagni D, Tibollo V, Dagliati A, Malovini A, Zambelli A, Napolitano C, Priori SG, Bellazzi R. Clinical and research data integration: the i2b2-FSM experience. AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:239-40. eCollection 2013. (pdf)

    Segagni D, Tibollo V, Dagliati A, Perinati L, Zambelli A, Priori S, Bellazzi R. The ONCO-I2b2 project: integrating biobank information and clinical data to support translational research in oncology. Stud Health Technol Inform. 2011;169:887-91. (link, pdf)

    Segagni D, Gabetta M, Tibollo V, Zambelli A, Priori SG, Bellazzi R. ONCO-i2b2: Improve patients selection through case-based information retrieval techniques. 8th International Conference on Data Integration in the Life Sciences, DILS 2012 (link)



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